Streefkerk J G, Deelder A M, Kors N, Kornelis D
J Immunol Methods. 1975 Sep;8(3):251-6. doi: 10.1016/0022-1759(75)90118-0.
Small amounts of antigen-coupled beads adherent to object slides provide a simple, quick, economical and sensitive immunohistochemical means of detecting antibodies in serum by both immunofluorescence and immunohistoperoxidase procedures. Sensitivity increases with decreasing quantities of antigen-coupled beads, as was demonstrated in the fluorescence procedure.