Cohen M D
Br J Radiol. 1979 Dec;52(624):942-4. doi: 10.1259/0007-1285-52-624-942.
The dose of contrast to be used for IV urography in neonates and infants is discussed. Toxic levels are only just above the currently accepted doses of 2-4.4 ml contrast medium per kg bodyweight. The dangers of expressing the dose of contrast medium as a volume of contrast related to the patient's age are discussed. A case is presented who had a severe reaction following an acceptable dose expressed as volume for age, but probably excessive when expressed as ml per kg bodyweight. It is concluded that for IV urography in neonates and infants the dose of contrast must be related to weight of patient and not its age; no dehydration should be used; and the injection should be slow, taking about three minutes.
讨论了新生儿和婴儿静脉尿路造影中使用的造影剂剂量。中毒水平仅略高于目前每公斤体重2 - 4.4毫升造影剂的公认剂量。讨论了将造影剂剂量表示为与患者年龄相关的造影剂体积的危险性。介绍了一个病例，该病例在按照年龄体积表示为可接受剂量后发生了严重反应，但按每公斤体重毫升数表示时可能过量。得出结论，对于新生儿和婴儿的静脉尿路造影，造影剂剂量必须与患者体重相关，而非年龄；不应进行脱水；注射应缓慢，约需三分钟。
