Welsh M G, Hansen J T, Reiter R J
Cell Tissue Res. 1979;204(1):111-25. doi: 10.1007/BF00235168.
Morphometric analytical procedures were employed to study the pineal gland of the Mongolian gerbil following superior cervical ganglionectomy (SCGX). The purpose of this study was to define the effects of sympathetic denervation on the morphology of the gland at two time periods, 0500 and 1900 h (one hour before lights-on and lights-off, respectively). Fluorescence histochemistry was employed to determine catecholamine and indoleamine content in intact and denervated pineal glands. After SCGX, the pinealocytes decrease in size, concretions are prevented from forming, and the yellow fluorescence in the gland is lost. Following denervation a depression in the volume of most of the pinealocyte organelles, i.e., SER, RER/ribosomes, free cytoplasm, mitochondria and presumptive secretory vesicles, was also observed. However, synaptic ribbons increased in volume in the gerbils that had been killed at 1900 h. It appears that the sympathetic innervation to the pineal gland is a requirement for the presumptive secretory activity of the pinealocytes.
采用形态计量分析方法研究颈上神经节切除术后（SCGX）蒙古沙鼠的松果体。本研究的目的是确定在两个时间段，即05:00和19:00（分别在开灯前和关灯前1小时），交感神经去神经支配对腺体形态的影响。采用荧光组织化学法测定完整和去神经支配的松果体中儿茶酚胺和吲哚胺的含量。SCGX后，松果体细胞体积减小，结石形成受阻，腺体中的黄色荧光消失。去神经支配后，还观察到大多数松果体细胞细胞器的体积减小，即滑面内质网、粗面内质网/核糖体、游离细胞质、线粒体和假定的分泌小泡。然而，在19:00处死的沙鼠中，突触带的体积增加。似乎松果体的交感神经支配是松果体细胞假定分泌活动的必要条件。
