磺吡酮（“安妥明丙磺舒”）对血液粘度影响的研究。

A study of the effect of sulphinpyrazone ('Anturan') on blood viscosity.

作者信息

Johnston R V, Lowe G D, Drummond M M, Forbes C D, Prentice C R

出版信息

Curr Med Res Opin. 1979;6(4):271-3. doi: 10.1185/03007997909109436.

Abstract

A double-blind, placebo-controlled crossover study of the effect of sulphinpyrazone on blood viscosity and its determinants (haematocrit, plasma fibrinogen and plasma viscosity) was carried out in 7 healthy male volunteers. Apart from a transient rise in fibrinogen (p less than 0.05) after 3 days of sulphinpyrazone treatment, no significant change in viscosity factors was seen over a 14-day period.

摘要

在7名健康男性志愿者中进行了一项双盲、安慰剂对照的交叉研究，以观察磺吡酮对血液粘度及其决定因素（血细胞比容、血浆纤维蛋白原和血浆粘度）的影响。除了在磺吡酮治疗3天后纤维蛋白原有短暂升高（p<0.05）外，在14天的观察期内未发现粘度因子有显著变化。