利用质谱法鉴定异恶唑基青霉素的活性代谢物。
Identification of the active metabolites of the isoxazolylpenicillins by means of mass-spectrometry.
作者信息
Thijssen H H
出版信息
J Antibiot (Tokyo). 1979 Oct;32(10):1033-7. doi: 10.7164/antibiotics.32.1033.
PMID:528362
Abstract
Electron-impact mass-spectrometry of the methyl esters of the isoxazolylpenicillins and of their active metabolites showed the latter to be formed from their parent compounds by hydroxylation of the 5-methyl group.
摘要
异恶唑基青霉素及其活性代谢产物的甲酯的电子轰击质谱表明，后者是由其母体化合物通过5-甲基的羟基化作用形成的。
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