在10 - 500伦琴X射线剂量范围内对成熟果蝇卵母细胞进行易位诱导。
Induction of translocations in mature Drosophila oocytes over a dose range of 10-500 Roentgens of x-rays.
作者信息
Abrahamson S, Gullifor P, Sabol E, Voigtlander J
出版信息
Proc Natl Acad Sci U S A. 1971 Jun;68(6):1095-7. doi: 10.1073/pnas.68.6.1095.
Abstract
Data are presented that demonstrate that a dose of 10 R of x-rays to mature oocytes in Drosophila causes a significant increase, more than double the spontaneous frequency, of inherited translocations. The dose-frequency relationship appears to fit best a linear response between 10 and 50 R. From 50 to 500 R, the frequency of rearrangements increases at the conventional dose 3/2 relationship.
摘要
所呈现的数据表明，对果蝇成熟卵母细胞施加10伦琴的X射线剂量会导致遗传易位的显著增加，其频率超过自发频率的两倍。剂量-频率关系在10至50伦琴之间似乎最符合线性响应。从50至500伦琴，重排频率以传统的剂量3/2关系增加。
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