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[新型生物抗真菌剂匹马霉素治疗孕期阴道念珠菌病]

[Treatment of vaginal moniliasis during pregnancy with a new biologic antifungal agent: pimaricin].

作者信息

Bernard G, Jerome M A

出版信息

Can Med Assoc J. 1966 Jul 30;95(5):215-8.

PMID:5296471
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1936777/
Abstract

Pregnancy creates conditions which favour the development and persistence of candidiasis (moniliasis). The resultant vaginitis is often refractory to treatment. A new fungicidal antibiotic, pimaricine (Pimafucine), was studied in 91 women with vaginal moniliasis, all of whom were pregnant. Fifty-six (63%) were cured on the basis of negative cultures and 28 became symptomfree in spite of positive cultures. In this series, 94.3% benefited from treatment.

摘要

怀孕会创造有利于念珠菌病(念珠菌性阴道炎)发展和持续存在的条件。由此引发的阴道炎往往难以治疗。一种新型杀真菌抗生素匹马菌素(皮马菌素)在91名患有阴道念珠菌病的孕妇中进行了研究。根据培养结果阴性,56名(63%)患者治愈,尽管培养结果为阳性,但仍有28名患者症状消失。在这个系列研究中,94.3%的患者从治疗中获益。

相似文献

1
[Treatment of vaginal moniliasis during pregnancy with a new biologic antifungal agent: pimaricin].[新型生物抗真菌剂匹马霉素治疗孕期阴道念珠菌病]
Can Med Assoc J. 1966 Jul 30;95(5):215-8.
2
[Effect of Pimaricin on vaginal trichomoniasis].
J Antibiot B. 1967 Aug;20(4):281-4.
3
[Clinical use of pimaricin in gynecology and obstetrics].匹马霉素在妇产科的临床应用
J Antibiot B. 1965 Dec;18(6):486-90.
4
[Effect of pimaricin vaginal tablets on vaginal candidiasis].匹马霉素阴道片对阴道念珠菌病的疗效
J Antibiot B. 1965 Oct;18(5):377-9.
5
[Therapeutic results with pimaricin in trichomonas and monilial vaginitis].[匹马霉素治疗滴虫性和念珠菌性阴道炎的疗效]
J Antibiot B. 1965 Dec;18(6):491-4.
6
[The treatment of vaginal candidiasis with pimaricin, a new antibiotic fungicide].[用新抗生素杀真菌剂匹马霉素治疗阴道念珠菌病]
Brux Med. 1961 Mar 26;41:421-4.
7
"Pimafucin" for the treatment of moniliasis: a clinical trial.用“匹马菌素”治疗念珠菌病:一项临床试验。
Med J Aust. 1967 Feb 25;1(8):382-3. doi: 10.5694/j.1326-5377.1967.tb21280.x.
8
[Use of pimaricin in the therapy of mycotic-protozoal vulvovaginitis].制霉菌素在真菌-原虫性外阴阴道炎治疗中的应用
Minerva Ginecol. 1970 Jun 15;22(11):584-7.
9
[On the clinical use of a new antibiotic, pimaricin, in the therapy of vaginitis caused by Candida albicans and by Trichomonas].
Quad Clin Ostet Ginecol. 1966 Nov;21(11):929-45.
10
[Action of pimaricin on postpartum mycoses].[匹马霉素对产后真菌病的作用]
Lyon Med. 1966 Nov 20;216(47):1179-83.

引用本文的文献

1
[Candida albicans vaginitis: clinical aspects and chlordantoin therapy].[白色念珠菌性阴道炎:临床症状与氯丹妥因疗法]
Can Med Assoc J. 1968 Aug 3;99(5):211-3.
2
[Pimaricin therapy in mycotic complications of hemoblastosis].[制霉菌素治疗造血系统疾病的真菌并发症]
Blut. 1972 Mar;24(3):180-3. doi: 10.1007/BF01631467.
3
Cure and relapse with antifungal therapy.抗真菌治疗的治愈与复发
Proc R Soc Med. 1977;70 Suppl 4(Suppl 4):24-32. doi: 10.1177/00359157770700S407.

本文引用的文献

1
A new agent for the treatment of vaginal candidiasis.一种治疗阴道念珠菌病的新药。
Am J Obstet Gynecol. 1959 Dec;78:1320-3. doi: 10.1016/0002-9378(59)90599-x.
2
NEW ANTIFUNGAL ANTIBIOTIC PREPARATION: CLINICAL DOSE STUDY.新型抗真菌抗生素制剂:临床剂量研究。
Am J Obstet Gynecol. 1964 Oct 1;90:370-3.
3
THE PATHOGENICITY OF CANDIDA SPECIES IN THE HUMAN VAGINA.
J Obstet Gynaecol Br Commonw. 1964 Oct;71:692-5. doi: 10.1111/j.1471-0528.1964.tb04341.x.
4
[THE TREATMENT OF MYCOTIC VAGINITIS WITH A NEW ANTIBIOTIC: PIMARICINE].[一种新型抗生素——匹马菌素治疗霉菌性阴道炎]
Rev Fr Gynecol Obstet. 1963 Sep-Oct;58:635-47.
5
Vulvovaginal moniliasis (candidiasis) in pregnancy.妊娠期外阴阴道念珠菌病(念珠菌病)
Obstet Gynecol. 1963 Feb;21:206-9.
6
Pimaricin, a new antifungal antibiotic.
Antibiot Annu. 1957;5:878-85.
7
Identification of and therapy for vaginal candidiasis.阴道念珠菌病的识别与治疗
Am J Obstet Gynecol. 1957 Jul;74(1):42-6. doi: 10.1016/s0002-9378(16)37001-6.
8
Nystatin vaginal tablets in the treatment of candidal vulvovaginitis.制霉菌素阴道片治疗念珠菌性外阴阴道炎。
Obstet Gynecol. 1956 Sep;8(3):364-7.
9
[Fungicidal antibiotics, produced by Actinomycetes, candicidin].[由放线菌产生的杀真菌抗生素,制霉菌素]
Presse Med (1893). 1953 Oct 17;61(66):1327-8.