Bernard G, Jerome M A
Can Med Assoc J. 1966 Jul 30;95(5):215-8.
Pregnancy creates conditions which favour the development and persistence of candidiasis (moniliasis). The resultant vaginitis is often refractory to treatment. A new fungicidal antibiotic, pimaricine (Pimafucine), was studied in 91 women with vaginal moniliasis, all of whom were pregnant. Fifty-six (63%) were cured on the basis of negative cultures and 28 became symptomfree in spite of positive cultures. In this series, 94.3% benefited from treatment.
怀孕会创造有利于念珠菌病(念珠菌性阴道炎)发展和持续存在的条件。由此引发的阴道炎往往难以治疗。一种新型杀真菌抗生素匹马菌素(皮马菌素)在91名患有阴道念珠菌病的孕妇中进行了研究。根据培养结果阴性,56名(63%)患者治愈,尽管培养结果为阳性,但仍有28名患者症状消失。在这个系列研究中,94.3%的患者从治疗中获益。