Guld J
Bull World Health Organ. 1966;35(4):479-82.
The frequent experience in the tropics of poor results of BCG vaccination is sometimes explained by a hypothetical interaction with "non-specific" tuberculin sensitivity. However, samples of data from five tropical countries, reported in this paper, demonstrate a slight, positive correlation between the individual tuberculin allergy before and after vaccination. A negative correlation might have been expected had the "non-specific" allergy been the cause of the poor vaccination results, and this particular hypothesis is therefore rejected.
卡介苗接种在热带地区常常效果不佳,这一现象有时被解释为与“非特异性”结核菌素敏感性存在假设性相互作用。然而,本文报告的来自五个热带国家的数据样本表明,接种前后个体结核菌素过敏之间存在轻微的正相关。如果“非特异性”过敏是接种效果不佳的原因,本应出现负相关,因此这一特定假设被否定。