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波利尼西亚人中的肺部钙化以及皮肤对结核菌素、组织胞浆菌素和球孢子菌素的敏感性。

Pulmonary calcification and skin sensitivities to tuberculin, histoplasmin and coccidioidin among Polynesians.

作者信息

Han E S

出版信息

Bull World Health Organ. 1966;35(4):527-33.

Abstract

Pulmonary calcifications are fairly common in Western Samoa, but they cannot be attributed entirely to tuberculosis, since they are also produced by certain systemic mycoses and parasitic infestations. Furthermore, in many tropical areas, skin sensitivity to tuberculin is often due to certain unidentified weak sensitizing agents, rather than to the usual virulent tubercle bacilli.Skin sensitivity to histoplasmin and coccidioidin is absent in both Western Samoa and the Tokelau Islands; consequently, pulmonary calcifications found in these places cannot be attributed to either histoplasmosis or coccidioidomycosis.Both Western Samoans and Tokelauans exhibit non-specific reactions to tuberculin throughout their lives, but these reactions are clearer and more distinct in groups aged 15 years or more.The prevalence of non-specific sensitivity to tuberculin should be investigated further.

摘要

肺钙化在西萨摩亚相当常见,但它们不能完全归因于结核病,因为某些全身性真菌病和寄生虫感染也会导致肺钙化。此外,在许多热带地区,皮肤对结核菌素的敏感性往往是由某些不明的弱致敏剂引起的,而不是由常见的强毒结核杆菌引起的。西萨摩亚和托克劳群岛的居民对组织胞浆菌素和球孢子菌素均无皮肤敏感性;因此,在这些地方发现的肺钙化不能归因于组织胞浆菌病或球孢子菌病。西萨摩亚人和托克劳人一生都对结核菌素表现出非特异性反应,但这些反应在15岁及以上的人群中更明显、更清晰。对结核菌素非特异性敏感性的患病率应进一步调查。

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本文引用的文献

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Epidemiological aspects of histoplasmin, tuberculin and coccidioidin sensitivity.
Am J Hyg. 1951 Jan;53(1):33-57. doi: 10.1093/oxfordjournals.aje.a119435.
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Histoplasmin testing in different geographic areas.不同地理区域的组织胞浆菌素检测。
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