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人类葡萄糖-6-磷酸脱氢酶的命名

Nomenclature of glucose-6-phosphate dehydrogenase in man.

出版信息

Bull World Health Organ. 1967;36(2):319-22.

PMID:5299754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2476388/
Abstract

The World Health Organization convened in Geneva from 5 to 10 December 1966 a Scientific Group on Standardization of Procedures for the Study of Glucose-6-Phosphate Dehydrogenase(1) (EC 1.1.1.49; D-glucose-6-phosphate: NAPD oxidoreductase; G6PD). Variants of this enzyme have attracted international attention both as causes of various haemolytic disorders and as useful genetic markers in man. In the course of the meeting the variants of this enzyme thus far described were extensively reviewed. There was unanimous agreement that a consistent system of nomenclature would be desirable, and that as G6PD variants were only one example of similar polymorphisms in man, a nomenclature should be devised which might conceivably be applied to other enzymes.The Group included the following recommendations on nomenclature in its report, which will be published in full in World Health Organization: Technical Report Series, 1967, 366.

摘要

世界卫生组织于1966年12月5日至10日在日内瓦召开了一次关于葡萄糖-6-磷酸脱氢酶(1)(EC 1.1.1.49;D-葡萄糖-6-磷酸:NAPD氧化还原酶;G6PD)研究程序标准化的科学小组会议。这种酶的变体作为各种溶血性疾病的病因以及人类有用的遗传标记已引起国际关注。在会议过程中,对迄今为止所描述的这种酶的变体进行了广泛的审查。与会者一致认为,需要一个一致的命名系统,而且由于G6PD变体只是人类类似多态性的一个例子,应设计一种命名法,设想该命名法可应用于其他酶。该小组在其报告中列入了以下关于命名法的建议,该报告将全文发表在《世界卫生组织:技术报告系列,1967年,第366号》中。