Hammerer I
Padiatr Padol. 1979;14(4):381-92.
The author reviewed the complications of 700 heart catheterizations in infants and children performed between 1970 and 1978 with a frequency of 55 to 113 investigations per year. Arrhythmias occurred on 70 occasions (10%), death within 24 hours: 14 (2%), extravasation of contrast media: 11 (1,6%), perforation by catheter: 6 (0,9%), cyanotic spells 5 (0,7%), myocardial ischemia: 4 (0,6%), respiratory arrest: 4 (0,6%), convulsions: 2 (0,3%), wound infection: 2 (0,3%), icterus 2 (0.3%), lung atelactasis: 1 (0,15%), bacterial endocarditis: 1 (0,15%), pyrexia: 1 (0,15%), exanthema: 1 (0,15%), pulmonary edema: 1 (0,15%), meningitis purulenta and hepatitis as possible complications: 1 (0,15%) each. The mortality figue of 2% lies well within the range of rates reported by Ho and ass. (1972): 1,5%, Stanger and ass. (1974): 3,0%, Rowe (1978): 0,95%, and Graham (1978): 2,9%. Mortality mainly occurs in sick neonates and infants with complex cardiac malformations. It could be lowered by a more aggressive approach to diagnostic work-up of suspected cardiac disease, as well as by using more sophisticated catheterization techniques and material and by introducing intensive care principles on the infant ward. Catheter related mortality (e. g. by perforation, severe arrhythmia) could be reduced to zero during the last three years. Myocardial staining by contrast media and electrocardiographic alterations suggesting myocardial ischemia occurred comparatively often but were never followed by serious or long lasting sequelae. Their occurrence was not related to the diagnosis or to the age of the patient. Respiratory arrest and convulsions could only be observed in sick infants. The seizures were not directly related to angiocardiography. All other complications were incidental events. Arrhythmias and vascular complications are discussed in separate papers.
作者回顾了1970年至1978年间对700例婴幼儿进行的心导管插入术的并发症情况,每年进行55至113例检查。心律失常发生70次(10%),24小时内死亡14例(2%),造影剂外渗11例(1.6%),导管穿孔6例(0.9%),青紫发作5例(0.7%),心肌缺血4例(0.6%),呼吸骤停4例(0.6%),惊厥2例(0.3%),伤口感染2例(0.3%),黄疸2例(0.3%),肺不张1例(0.15%),细菌性心内膜炎1例(0.15%),发热1例(0.15%),皮疹1例(0.15%),肺水肿1例(0.15%),可能的并发症如脓性脑膜炎和肝炎各1例(0.15%)。2%的死亡率处于Ho等人(1972年)报告的1.5%、Stanger等人(1974年)报告的3.0%、Rowe(1978年)报告的0.95%以及Graham(1978年)报告的2.9%的范围内。死亡主要发生在患有复杂心脏畸形的患病新生儿和婴儿中。通过对疑似心脏病进行更积极的诊断检查、使用更先进的心导管插入技术和材料以及在婴儿病房引入重症监护原则,死亡率可能会降低。在过去三年中,与导管相关的死亡率(如因穿孔、严重心律失常)可降至零。造影剂导致的心肌染色和提示心肌缺血的心电图改变相对常见,但从未导致严重或长期的后遗症。它们的发生与诊断或患者年龄无关。呼吸骤停和惊厥仅在患病婴儿中观察到。惊厥与心血管造影术无直接关系。所有其他并发症均为偶然事件。心律失常和血管并发症在单独的论文中讨论。