Henshaw D L, Fews A P, Webster D J
Phys Med Biol. 1979 Nov;24(6):1227-42. doi: 10.1088/0031-9155/24/6/013.
A technique for low-level alpha-particle autoradiography of bronchial epithelium utilising the plastic track detector, CR-39, is described. This plastic is new to the field of nuclear track detection and is very sensitive to alpha-particles. The recording properties of CR-39 for alpha-particles are described in detail and the technique for autoradiography discussed. This technique includes two methods of background reduction enabling activities as low as 2 alpha-particles cm-2 to be detected. The location of the point of emission of an alpha-particle from the tissue surface can be determined to an accuracy of a few micrometers. Determination of the lower limit to the energy of individual alpha-particles is possible from measurements of their range in the plastic. Examples are given of the determination of the microdistribution of alpha-particle active nuclei in bronchial tissue including the observation of two 'hot-spots' in the epithelium sample which are attributed to the presence of small particles of uranium with its daughter products.
描述了一种利用塑料径迹探测器CR - 39对支气管上皮进行低水平α粒子放射自显影的技术。这种塑料在核径迹探测领域是新的，对α粒子非常敏感。详细描述了CR - 39对α粒子的记录特性，并讨论了放射自显影技术。该技术包括两种降低背景的方法，能够检测低至2个α粒子/cm²的活度。从组织表面发射α粒子的点的位置可以精确到几微米。通过测量α粒子在塑料中的射程，可以确定单个α粒子能量的下限。给出了在支气管组织中确定α粒子活性核微分布的例子，包括在上皮样本中观察到两个“热点”，这归因于含有其子产物的小铀颗粒的存在。
