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高渗性非酮症糖尿病昏迷:特别涉及血管并发症

Hyperosmolar non-ketotic diabetic coma: with particular reference to vascular complications.

作者信息

Whelton M J, Walde D, Havard C W

出版信息

Br Med J. 1971 Jan 9;1(5740):85-6. doi: 10.1136/bmj.1.5740.85.

Abstract

Two West Indian men with no previous history of diabetes mellitus developed hyperosmolar non-ketotic diabetic coma. Intra-abdominal catastrophes secondary to mesenteric thrombosis played a major part in the death of these patients, in both of whom control of the hyperosmolar state had been achieved. Both patients had evidence of infarction of intestine at necropsy. Vascular thromboses are a major complication of this form of coma and must be considered when such patients develop signs of an acute abdomen.

摘要

两名既往无糖尿病病史的西印度男性发生了高渗性非酮症糖尿病昏迷。肠系膜血栓形成继发的腹腔内灾难在这些患者的死亡中起了主要作用,这两名患者的高渗状态均已得到控制。尸检时两名患者均有肠梗死的证据。血管血栓形成是这种昏迷形式的主要并发症,当这类患者出现急腹症体征时必须予以考虑。

引用本文的文献

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DKA and thrombosis.糖尿病酮症酸中毒与血栓形成
CMAJ. 2005 Jul 19;173(2):132; author reply 132-3. doi: 10.1503/cmaj.1050103.
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Management of hyperosmolar coma.高渗性昏迷的管理
J R Soc Med. 1980 Feb;73(2):134-8. doi: 10.1177/014107688007300211.
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Haemostatic changes in diabetic coma.糖尿病昏迷中的止血变化。
Diabetologia. 1981 Sep;21(3):172-7. doi: 10.1007/BF00252650.

本文引用的文献

1
Gastric hemorrhage in diabetic coma.
Diabetes. 1960 Mar-Apr;9:94-6. doi: 10.2337/diab.9.2.94.
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Arch Intern Med. 1965 Jul;116:74-82.
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Lancet. 1963 Jan 12;1(7272):75-7. doi: 10.1016/s0140-6736(63)91082-1.
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Hyperglycemia and hyperosmolarity in an eighteen-month-old child.
N Engl J Med. 1967 Mar 23;276(12):683-4. doi: 10.1056/NEJM196703232761208.
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Gastrointestinal manifestations of diabetes.糖尿病的胃肠道表现
N Engl J Med. 1966 Dec 15;275(24):1350-61. doi: 10.1056/NEJM196612152752406.
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Hyperosmolar coma.
Am J Med. 1968 Oct;45(4):485-7. doi: 10.1016/0002-9343(68)90164-2.

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