Dorval C, Brown A W
Bull World Health Organ. 1970;43(5):727-34.
The insecticide fenthion, which shows great promise for controlling the filariasis vector Culex pipiens fatigans, has been found in the laboratory to induce a certain amount of resistance. As the biochemical nature of fenthion resistance was known to be due to an increase in a particular esterase activity, the inheritance of the character was investigated in the present study. It was found to be mainly due to a single slightly recessive gene associated with linkage-group 2, and the increase in detoxifying esterase activity showed a similar inheritance.
杀虫剂倍硫磷在控制丝虫病传播媒介致倦库蚊方面显示出巨大潜力,但在实验室中已发现它会诱导一定程度的抗性。由于已知倍硫磷抗性的生化本质是由于一种特定酯酶活性的增加,因此在本研究中对该性状的遗传进行了调查。结果发现,它主要归因于与第2连锁群相关的一个单一的轻度隐性基因,解毒酯酶活性的增加也显示出类似的遗传方式。