Dehen H, Cambier J
Rev Neurol (Paris). 1979 Oct;135(8-9):573-82.
The impossibility of voluntary closing of the eyelids is usually reported in the published literature as being associated with bilateral cerebral lesions. In the three cases reported by the authors, this rare symptom was caused by unilateral lesions of the right hemisphere. The inability to close the eyelids voluntarily is, with these types of lesion, a transient sign which is rapidly replaced by difficulty in maintaining the consign. The physiopathology of motor impersistence (neglect of instructions), and of absence of voluntarily closing of the eyelids may be connected. Two associated mechanisms are discussed : preferential activation of the left hemisphere during a verbal consign and a fault in interhemispheric inhibition.
眼睑自主闭合障碍在已发表的文献中通常被报道与双侧脑损伤有关。在作者报告的3例病例中，这种罕见症状是由右半球单侧损伤引起的。对于这类损伤，眼睑自主闭合障碍是一种短暂的体征，很快就会被维持指令的困难所取代。运动不能持续（忽视指令）和眼睑自主闭合障碍的生理病理学可能存在关联。文中讨论了两种相关机制：言语指令过程中左半球的优先激活以及半球间抑制缺陷。
