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革兰氏阴性厌氧菌及其他相关细菌菌株引起的感染

[Infections caused by gram negative anaerobic bacteria and other associated bacterial strains].

作者信息

Tamayo y Orozco J A, Ruiloba Benítez J, Ojeda F

出版信息

Rev Gastroenterol Mex. 1979 Jul-Sep;44(3):147-53.

PMID:531438
Abstract

Between November 1975--December 1977, in the Laboratory of Microbiology, National Institute of Nutrition, Mexico, 156 cultures for anaerobic bacteria were grown on 118 cases with a clinical picture suggestive of anaerobic infection. There were 42 positive cultures (26.9%) from which 18 (42.8%) grew a mixed flora (aerobicanaerobic). Those 42 cultures came from 35 patients (29.6%) and the 18 mixed cultures came from 18 cases (15.25% global and 51.42% of the cases with anaerobic flora). The highest positive marks were obtained from material provenient from the abdominal cavity, and lesser indexes were obtained from lungs, blood, bone and sinovial cavities. The overall mortality was registered in 24 cases (20.33%) but only in 6 cases (5.8% global and 25% of the total cases) a positive anaerobic culture was obtained. In these 6 cases the cause of death was secondary to the principal disease, and only in one case the patient died from septicemia. The diagnosis of anaerobic infection resides mainly in the clinical findings, secondly in a positive gram stain, and thirdly in the identification of the etiologic agent, that will aid in the choice of a more specific therapy, which must include a surgical excision of the affected tissues.

摘要

1975年11月至1977年12月期间,在墨西哥国家营养研究所微生物实验室,对118例临床症状提示厌氧菌感染的患者培养了156株厌氧菌。有42份培养物呈阳性(26.9%),其中18份(42.8%)培养出混合菌群(需氧菌-厌氧菌)。这42份培养物来自35名患者(29.6%),18份混合培养物来自18例患者(占全部病例的15.25%,占厌氧菌感染病例的51.42%)。腹腔来源的标本阳性率最高,而肺部、血液、骨骼和滑膜腔来源的标本阳性率较低。共有24例患者死亡(20.33%),但仅6例(占全部病例的5.8%,占厌氧菌培养阳性病例总数的25%)获得了厌氧菌培养阳性结果。在这6例中,死亡原因均为主要疾病的继发结果,仅1例患者死于败血症。厌氧菌感染的诊断主要依据临床表现,其次是革兰氏染色阳性,第三是病原体鉴定,这将有助于选择更具针对性的治疗方法,其中必须包括对受感染组织进行手术切除。

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