各种抗淋巴细胞血清（ALS）对脾细胞碎片迁移的影响。
The effect of various antilymphocyte sera (ALS) on the migration of spleen fragment cells.
作者信息
Svejcar J, Pekárek J, Johanovský J
出版信息
Immunology. 1971 Jul;21(1):45-9.
The effect of various antilymphocyte sera (ALS) on the migration activity of cells from spleen fragments was studied. It was demonstrated that the ALS inhibited spleen cell migration in very high dilutions. This inhibitory effect could only be demonstrated on the homologous system, i.e. only on spleen fragments of the animal species against which the ALS was prepared. Sera from various animal species used as controls did not influence the migration of the rabbit and guinea-pig spleen cells. Other antisera were also tested for their ability to influence the behaviour of spleen cells. The antipolymorph serum had a mild inhibitory effect as did the antiglobulin serum. The antimacrophage serum was potent but its effect was not so pronounced as that of the ALS.
研究了各种抗淋巴细胞血清（ALS）对脾组织碎片中细胞迁移活性的影响。结果表明，ALS在极高稀释度下可抑制脾细胞迁移。这种抑制作用仅在同源系统中得到证实，即仅对制备ALS所针对的动物物种的脾组织碎片有作用。用作对照的来自各种动物物种的血清不影响兔和豚鼠脾细胞的迁移。还测试了其他抗血清影响脾细胞行为的能力。抗多形核白细胞血清和抗球蛋白血清有轻微抑制作用。抗巨噬细胞血清作用较强，但其作用不如ALS明显。
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