Salmon P R, Branch R A, Collins C, Espiner H, Read A E
Gut. 1971 Sep;12(9):729-35. doi: 10.1136/gut.12.9.729.
Fifty-one patients with large bowel disease were examined with the Olympus CF-SB fibreoptic colonoscope. With adequate bowel preparation and employing inhalational analgesia administered by a self-demand valve the whole sigmoid colon could be examined in the majority of patients within 30 minutes. In 23% of cases (12/51) the diagnosis was either made or confirmed by this procedure alone. Fibreoptic sigmoidoscopy is especially helpful in patients with either equivocal or failed barium enemas and is indicated in patients with unexplained rectal bleeding, extending the search for polyps and cancer, and studying patients with inflammatory bowel disease.About one quarter of biopsies taken from a flat mucosal surface with the Olympus flexible biopsy forceps may be insufficient for detailed histology due to their small size. For this reason multiple biopsies may be taken. Adequate biopsies were always obtained from projecting lesions and could be very accurately sited. Colour photography employing automatic exposure control is used to supplement the information obtained. It is concluded that fibreoptic sigmoidoscopy is a valuable additional investigation in selected patients with suspected disease of the large bowel and to date has been without complications.
51例大肠疾病患者接受了奥林巴斯CF-SB纤维结肠镜检查。在肠道准备充分并使用按需阀门给予吸入性镇痛的情况下，大多数患者可在30分钟内完成整个乙状结肠的检查。在23%的病例（12/51）中，仅通过该检查就做出了诊断或证实了诊断。纤维乙状结肠镜检查对钡剂灌肠结果不明确或失败的患者特别有用，适用于不明原因直肠出血的患者、扩大息肉和癌症的检查范围以及研究炎症性肠病患者。使用奥林巴斯柔性活检钳从平坦黏膜表面获取的活检标本中，约四分之一可能因体积过小而不足以进行详细的组织学检查。因此，可能需要进行多次活检。从突出病变处总能获得足够的活检标本，且定位非常准确。采用自动曝光控制的彩色摄影用于补充所获得的信息。结论是，纤维乙状结肠镜检查对于选定的疑似大肠疾病患者是一项有价值的辅助检查，迄今为止尚未出现并发症。
