[应激状态下左心室射血分数的放射性核素测定：与心血管造影术的比较]

[Radionuclide determination of the left ventricular ejection fraction under stress: comparison with angiocardiography].

作者信息

Nüesch K, Hirzel H O, Pfeiffer A, Sialer G, Horst W, Krayenbühl H P

出版信息

Schweiz Med Wochenschr. 1979 Nov 10;109(43):1648-50.

Abstract

Left ventricular ejection fraction (LVEF) determined by first pass radionuclide (Nucl.) and biplane contrast angiocardiography (Angio.) was compared in 62 patients with suspected coronary artery disease under resting conditions and in 32/62 patients during bicycle ergometry at identical work load. At rest both methods correlated with r = 0.81 with similar heart rates in both determinations. The mean value of LVEF (Nucl.) was lower than the mean value of LVEF (Angio.), at 50 +/- 2 (SE) % and 58 +/- 2% respectively (p less than 0.001). During exercise a significant correlation between the two methods was again found (r = 0.76). This time no difference was detected between the mean values for LVEF (50 +/- 3% [Nucl.] vs 48 +/- 2% [Angio.], n.s.), which may be explained by the higher heart rates during the invasive study (123 +/- 5/min [Angio.] vs. 108 +/- 4/min [Nucl.], p less than 0.001), resulting in a higher degree of ischemia and hence a lower LVEF. The interobserver variability did not differ between the two methods.

摘要

在62例疑似冠心病患者静息状态下，以及在相同工作量的自行车运动试验中对其中32例患者，比较了首次通过放射性核素（Nucl.）和双平面造影心血管造影术（Angio.）测定的左心室射血分数（LVEF）。静息时，两种方法的相关性为r = 0.81，两次测定的心率相似。LVEF（Nucl.）的平均值低于LVEF（Angio.）的平均值，分别为50±2（SE）%和58±2%（p＜0.001）。运动期间，再次发现两种方法之间存在显著相关性（r = 0.76）。这次未检测到LVEF平均值之间的差异（50±3%[Nucl.]对48±2%[Angio.]，无显著性差异），这可能是由于侵入性研究期间心率较高（123±5/分钟[Angio.]对108±4/分钟[Nucl.]，p＜0.001），导致更高程度的缺血，从而LVEF较低。两种方法之间的观察者间变异性没有差异。