Dambacher M A, Fischer J A
Schweiz Med Wochenschr. 1979 Dec 8;109(47):1897-8.
The leading symptom in patients with primary hyperparathyroidism (pHPT) is renal lithiasis and not osteopathy. The most abundant circulating forms of parathyroid hormone in pHPT represent COOH-terminal fragments with molecular weights ranging from 4000 to 7000. Radioimmunnoassays making use of antibodies directed to CCOH-terminal parts of human parathyroid hormone are therefore suitable in distinguishing patients with pHPT from control subjects and patients with hypercalcemia unrelated to hyperfunctioning parathyroid glands.
原发性甲状旁腺功能亢进症（pHPT）患者的主要症状是肾结石而非骨病。pHPT患者中循环甲状旁腺激素最丰富的形式是分子量在4000至7000之间的COOH末端片段。因此，利用针对人甲状旁腺激素C末端部分的抗体进行放射免疫分析，适用于区分pHPT患者与对照受试者以及与甲状旁腺功能亢进无关的高钙血症患者。
