Wexler J P, Blaufox M D
Semin Nucl Med. 1979 Oct;9(4):310-9. doi: 10.1016/s0001-2998(79)80016-1.
Portable nonimaging probes have been developed that can evaluate left ventricular function using radionuclide techniques. Two modes of data acquisition are possible with these probe systems, first-pass and gated. Precordial radiocardiograms obtained after a bolus injection can be used to determine cardiac output, pulmonary transit time, pulmonary blood volume, left ventricle ejection fraction, and left-to-right shunts. Gated techniques can be used to determine left ventricular ejection fraction and sytolic time intervals. Probe-determined indices of left ventricular function agree excellently with comparable measurements determined by conventional camera-computer methods as well as by invasive techniques. These have begun to be used in a preliminary manner in a variety of clinical problems associated with left ventricular dysfunction. This review discusses the types of probe systems available, the methods used in positioning them, and details the specifics of their data acquisition and processing capacity. The major criticisms of probe methods are that they are nonimaging and that they measure global rather than regional left ventricular function. In spite of these criticisms, probe systems, because of their portability, high sensitivity, and relatively low cost are useful supplements to conventional camera-computer systems for the measurement of parameters of left ventricular performance using radionuclide techniques.
已开发出便携式非成像探头，可利用放射性核素技术评估左心室功能。这些探头系统有两种数据采集模式，即首次通过法和门控法。静脉注射后获得的心前区放射性心动图可用于测定心输出量、肺 transit 时间、肺血容量、左心室射血分数和左向右分流。门控技术可用于测定左心室射血分数和收缩时间间期。探头测定的左心室功能指标与传统相机 - 计算机方法以及侵入性技术测定的可比测量值非常吻合。这些已开始初步用于与左心室功能障碍相关的各种临床问题。本综述讨论了可用的探头系统类型、定位它们所使用的方法，并详细介绍了其数据采集和处理能力的细节。对探头方法的主要批评是它们是非成像的，并且它们测量的是整体而非局部左心室功能。尽管有这些批评，但由于其便携性、高灵敏度和相对低成本，探头系统对于使用放射性核素技术测量左心室性能参数而言，是传统相机 - 计算机系统的有用补充。
