Pedrique M R, Ercoli N
Bull World Health Organ. 1971;45(4):411-7.
This paper presents the results of a clinical study in which a new antimony preparation-a chelate of dimethylcysteine with antimony sodium tartrate ("NAP")-was administered intramuscularly at a total dosage of 2 g (5x400 mg, corresponding to 290 mg of Sb) to 400 patients with schistosomiasis. Among 108 patients in a rural population the treatment was on the whole well accepted (97% completed the intensive course of injections), thus indicating that NAP would be useful for the mass treatment of schistosomiasis.
本文介绍了一项临床研究的结果。该研究中，一种新的锑制剂——二甲基半胱氨酸与酒石酸锑钠的螯合物（“NAP”），以2克的总剂量（5×400毫克，相当于290毫克锑）肌肉注射给400名血吸虫病患者。在108名农村患者中，该治疗总体上被广泛接受（97%完成了强化注射疗程），这表明NAP可用于血吸虫病的大规模治疗。
