结肠手术。抗生素在术前准备中的作用。
Operations on the colon. The role of antibiotics in preoperative preparation.
作者信息
Gordon H E, Gaylor D W, Richmond D M, Clarke J S, Finegold S M
出版信息
Calif Med. 1965 Oct;103(4):243-6.
A study was carried out on 183 patients in an attempt to evaluate the role of antibiotics in the preoperative preparation of the colon.Kanamycin, neomycin and a placebo were administered in a double-blind fashion during a 72-hour period preceding operation. In addition, mechanical cleansing of the bowel was done in all cases. Considering only the criteria of mortality and the incidence of postoperative wound and peritoneal infections in this preliminary report there was no apparent significant difference between patients receiving antibiotics and those receiving a placebo.
对183名患者进行了一项研究，旨在评估抗生素在结肠术前准备中的作用。在手术前72小时内，以双盲方式给予卡那霉素、新霉素和一种安慰剂。此外，所有病例均进行了肠道机械清洁。在这份初步报告中，仅考虑死亡率以及术后伤口和腹腔感染的发生率，接受抗生素治疗的患者与接受安慰剂治疗的患者之间没有明显的显著差异。
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