Schraier M, Matute M L, Pest P S, Ogawa O, Parisow O
Acta Gastroenterol Latinoam. 1979;9(3):137-44.
Forty eight patients were evaluated to ascertain a correlation (if any) between gastric acid secretion, fasting and post prandial serum gastrin levels, gastric biopsy (antrum and fundus) and gastric emptying time after a standard test meal. The following conclusions were obtained: a) 57.8% of patients with atrophic gastritis and achlorhydria had evaluated serum gastrin levels; b) most patients with high gastrin levels had normal antrum on biopsy or showed only minimal inflamatory changes, while those with normal gastrin levels disclosed more pronounced histological changes; c) patients with achlorhydria had slower gastric emptying rates, and this was more evident among those with higher gastrin levels (though differences were not statistically significant). Further studies are required for a better understanding of the relationship between gastric emptying rate and gastrin levels in patients with chronic gastritis.
对48例患者进行了评估，以确定胃酸分泌、空腹和餐后血清胃泌素水平、胃活检（胃窦和胃底）与标准试餐后胃排空时间之间的相关性（如有）。得出以下结论：a）57.8%的萎缩性胃炎和胃酸缺乏患者检测了血清胃泌素水平；b）大多数胃泌素水平高的患者活检时胃窦正常或仅显示轻微炎症变化，而胃泌素水平正常的患者则有更明显的组织学变化；c）胃酸缺乏患者的胃排空率较慢，在胃泌素水平较高的患者中更为明显（尽管差异无统计学意义）。需要进一步研究以更好地理解慢性胃炎患者胃排空率与胃泌素水平之间的关系。
