Poonawalla F M, Iyengar M R
Appl Microbiol. 1965 Sep;13(5):755-6. doi: 10.1128/am.13.5.755-756.1965.
Treatment of a pharmaceutical preparation of vitamin B(12) and tetracycline with an ion-exchange resin by the batch method differentially adsorbed tetracycline, making possible a statistically reproducible microbiological assay of vitamin B(12) by the standard Escherichia coli plate method.
采用分批法用离子交换树脂处理维生素B₁₂和四环素的药物制剂,可选择性地吸附四环素,从而能够通过标准大肠杆菌平板法对维生素B₁₂进行统计学上可重复的微生物测定。