Oberman H A, Fidler W J
Am J Surg Pathol. 1979 Oct;3(5):387-95.
Twenty-five patients with tubular carcinoma of the breast were reviewed. All of the lesions were small, averaging 0.9 cm in diameter, and none exceeded 2.0 cm in diameter. Regardless of treatment, the prognosis proved favorable. Only three of the patients manifested axillary lymph nodal metastases, and none died of recurrent or metastatic neoplasm. These neoplasms frequently were associated with intraductal carcinoma and, to a lesser extent, with lobular carcinoma in situ. It is concluded that tubular carcinoma represents a slow-growing expression of invasive mammary carcinoma; nevertheless, it is likely that, if inadequately treated, these lesions will evolve into more common patterns of invasive carcinoma.
对25例乳腺管状癌患者进行了回顾性研究。所有病变均较小,平均直径为0.9厘米,且直径均未超过2.0厘米。无论采用何种治疗方法,预后均良好。只有3例患者出现腋窝淋巴结转移,且无患者死于复发或转移性肿瘤。这些肿瘤常与导管内癌相关,在较小程度上与小叶原位癌相关。结论是,管状癌是浸润性乳腺癌的一种生长缓慢的表现形式;然而,如果治疗不充分,这些病变可能会演变成更常见的浸润性癌模式。