Blesa Sánchez E
An Esp Pediatr. 1979 Dec;12(12):859-68.
The report deals with how the resection of the ileocaecal union, with or without caecum, and in diets of different fat levels, affects the absorption of various nutrients, the nitrogen balance, and the intestinal aerobic flora, in young pigs during periods of rapid growth. It describes the technical procedure and the results obtained from experiments on digestibility and the nitrogen balance, both in tests carried out in the immediate post-operative period and after four months; it was found that those animals operated on showed a lower protein, fat and gross fibre absorption, as well as a decrease in the percentage of nitrogen retained and efficiently used; in many cases the difference between operated and control animals was statistically significant. In those animals undergoing surgery changes occured in the intestinal aerobic flora: a greater number of germs were found in the jejunum, and a smaller number in the middle and distal ileum. The histological study of the ileocaecal union in these animals showed great similarity to the same area in man. Author attributes changes to the loss of valve and sphincter function in the removed area.
该报告探讨了在快速生长阶段的幼猪中,切除回盲部结合处(无论是否连带盲肠)以及不同脂肪水平的日粮,对各种营养物质吸收、氮平衡和肠道需氧菌群的影响。报告描述了技术操作过程以及在术后即刻和四个月后进行的消化率和氮平衡实验所获得的结果;结果发现,接受手术的动物蛋白质、脂肪和粗纤维吸收较低,氮保留和有效利用率百分比也有所下降;在许多情况下,手术动物与对照动物之间的差异具有统计学意义。接受手术的动物肠道需氧菌群发生了变化:空肠中发现的细菌数量更多,回肠中部和远端的细菌数量较少。对这些动物回盲部结合处的组织学研究表明,与人类同一区域非常相似。作者将这些变化归因于切除区域瓣膜和括约肌功能的丧失。