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髓质受压提示存在硬膜外结节性淋巴瘤(作者译)

[Medullary compression revealing the presence of an epidural nodular lymphoma (author's transl)].

作者信息

Cayla J, Rondier J, Pradat P, Hanau J

出版信息

Ann Med Interne (Paris). 1979;130(10):467-74.

PMID:533064
Abstract

A case of medullary compression is reported which was found to be due to an epidural lymphoma of the nodular type, which was centrofollicular, with only slight lymphocytic differentiation, and appeared to be isolated. The hour-glass appearance of the tumour suggested, however, that it was not the primary tumour. The short term outcome appeared to be favourable after surgery and radiotherapy but a limited period of chemotherapy is being given. Reports on the frequency of medullary compression during malignant non-Hodgkinson lymphomas vary between 1 and 15% of cases, and many cases have revealed the actual cause, especially in neurosurgical practice. Most authors do not accept the existence of lymphomas primarily located in the epidural space, and feel that they result from metastatic invasion or by contiguity. Prolonged survival can be hoped for after mixed treatment of these tumours, especially in histologically favourable forms.

摘要

报告了一例髓质受压病例,发现其病因是结节型硬膜外淋巴瘤,该淋巴瘤为中心滤泡性,仅有轻微淋巴细胞分化,且似乎为孤立性。然而,肿瘤的沙漏样外观提示它并非原发性肿瘤。手术和放疗后短期预后似乎良好,但正在进行有限疗程的化疗。关于恶性非霍奇金淋巴瘤期间髓质受压频率的报道在病例的1%至15%之间有所不同,许多病例已揭示实际病因,尤其是在神经外科实践中。大多数作者不接受主要位于硬膜外间隙的淋巴瘤的存在,认为它们是转移性侵袭或连续性侵犯所致。对这些肿瘤进行综合治疗后有望延长生存期,尤其是组织学表现良好的类型。

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