Legouix J P, Pierson A, Minot J F
Ann Otolaryngol Chir Cervicofac. 1979 Dec;96(12):821-6.
It is classically considered that cochlear fatigue and acoustic trauma occur when intensity is such that the ear is saturated, i.e. when the microphonic potential fails to increase in a linear fashion in relation to intensity and when distorsion appears. The present report concerns a study in the guinea pig of the relationship between the non-linearity of microphonic responses, and their fatigability. The results show that fatigability is related not only to non-linearity but also to the asymmetry of responses. The asymmetry of microphonic responses may be interpreted as reflecting an asymmetrical ionic flow at the upper pole of hair cells, resulting in an accumulation of potassium ions within and around hair cells and thereby creating a depression of responses.
传统观点认为，当强度达到使耳朵饱和的程度时，即当微音器电位不再随强度呈线性增加且出现畸变时，会发生耳蜗疲劳和声学创伤。本报告涉及一项关于豚鼠微音器反应的非线性与其易疲劳性之间关系的研究。结果表明，易疲劳性不仅与非线性有关，还与反应的不对称性有关。微音器反应的不对称性可能被解释为反映了毛细胞上极的离子流不对称，导致钾离子在毛细胞内和周围积聚，从而使反应减弱。
