淋巴细胞抗血清：犬肾同种异体移植的长期存活
Antiserum to lymphocytes: prolonged survival of canine renal allografts.
作者信息
Monaco A P, Abbott W M, Othersen H B, Simmons R L, Wood M L, Flax M H, Russell P S
出版信息
Science. 1966 Sep 9;153(3741):1264-7. doi: 10.1126/science.153.3741.1264.
PMID:5331415
Abstract
A horse immunized with dog lynmphocytes produced an antiserum which agglutinated canine lymphocytes in vitro and caused prolonged lymphopenia in dogs in vivo. Renal transplants in dogs treated with this antiserum survived for long periods, two of the grafts surviving beyond 350 days with normal function and histologic appearance.
摘要
用犬淋巴细胞免疫的一匹马产生了一种抗血清，该抗血清在体外能凝集犬淋巴细胞，在体内能使犬发生持续性淋巴细胞减少。用这种抗血清处理的犬的肾移植存活了很长时间，其中两个移植物存活超过350天，功能和组织学外观正常。
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