Urzua J, Irarrazaval M, Moran S, Maturana G, Valdés F, Quiroga M, Allende M, Dubernet J
Artif Organs. 1979 Nov;3(4):361-4. doi: 10.1111/j.1525-1594.1979.tb01078.x.
One hundred consecutive patients undergoing open-heart surgery were subjected to a prospective protocol designed for reduction of homologous blood utilization. The main points of this protocol were careful surgical hemostasis, normovolemic hemodilution, and retransfusion of blood lost to the operating field. It included use of the new Bentley BOS-10 Spiraflo oxygenator (Bentley Laboratories, Inc., Irvine, California, U.S.A.). The patients' ages ranged from 6 to 68 years and their weights from 18 to 84 kg. Fifty-four patients were subjected to valvular surgery, 30 to coronary revascularization, 13 to congenital defects repair, and 3 to resection of atrial myxomas. All patients could be weaned from bypass without receiving any blood. Eighty patients completed their surgery, and 60 were discharged from the intensive care unit without receiving any homologous blood or its derivatives. Total blood usage for the series throughout the entire stay in hospital was 1.32 units/patient, which included six reoperations for excessive bleeding. This reduction in blood utilization was achieved without excessive hemodilution and did not produce significant complications.
连续100例接受心脏直视手术的患者接受了一项旨在减少同源血使用的前瞻性方案。该方案的要点是仔细的手术止血、正常血容量血液稀释以及回输手术野失血。方案包括使用新型Bentley BOS - 10螺旋式氧合器（美国加利福尼亚州欧文市Bentley实验室公司）。患者年龄在6至68岁之间，体重在18至84千克之间。54例患者接受瓣膜手术，30例接受冠状动脉血运重建，13例接受先天性缺陷修复，3例接受心房黏液瘤切除。所有患者在未接受任何血液的情况下均可脱离体外循环。80例患者完成手术，60例在未接受任何同源血或其衍生物的情况下从重症监护病房出院。该系列患者在整个住院期间的总用血量为1.32单位/患者，其中包括6例因出血过多而进行的再次手术。在不过度血液稀释的情况下实现了血液使用量的减少，且未产生明显并发症。
