Among the drugs, which are topically administered, only epinephrine may produce retinal changes (macular oedema) in aphakic patients. Among the drugs, which are systemically administered, some immunodepressors, ethambutol, indomethacine, digitalis, but particularly chlorpromazine, thioridazine, quinine and chloroquine may produce toxic retinopathies. Concerning the intraocular metallic foreign bodies, siderosis is much more toxic for the retina than chalcosis.
在局部给药的药物中，只有肾上腺素可能会在无晶状体患者中引起视网膜变化（黄斑水肿）。在全身给药的药物中，一些免疫抑制剂、乙胺丁醇、吲哚美辛、洋地黄，尤其是氯丙嗪、硫利达嗪、奎宁和氯喹可能会导致中毒性视网膜病变。关于眼内金属异物，铁锈症对视网膜的毒性比铜锈症大得多。
