Genetic recombination in Escherichia coli: clone heterogeneity and the kinetics of segregation.

Several recombinant types may be produced from a single Escherichia coli zygote when the donor parent is Hfr-Hayes and segregation is delayed; usually only one type is produced with Hfr-Cavalli. Statistical experiments confirm well-known pedigree analyses by micromanipulation and suggest that DNA synthesis is required before final genetic integration.