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A clinical trial of thiocarlide (4-4' diisoamyloxythiocarbanilide).

作者信息

Urbancik B

出版信息

Tubercle. 1966 Sep;47(3):283-8. doi: 10.1016/s0041-3879(66)80007-7.

DOI:10.1016/s0041-3879(66)80007-7
PMID:5339425
Abstract
摘要

相似文献

1
A clinical trial of thiocarlide (4-4' diisoamyloxythiocarbanilide).硫卡利德(4-4′-二异戊氧基硫代碳酰替苯胺)的一项临床试验。
Tubercle. 1966 Sep;47(3):283-8. doi: 10.1016/s0041-3879(66)80007-7.
2
[Clinical observations on the use of 4-4'-diisoamyloxythiocarbanilide (Isoxy) in the therapy pulmonary tuberculosis].[4-4'-二异戊氧基硫代碳酰苯胺(异氧)治疗肺结核的临床观察]
Arch Tisiol Mal Appar Respir. 1967 Jun;22(6):590-608.
3
[Clinical experiences with a new antitubercular drug: 4,4'-diisoamyloxythiocarbanilide (isoxyl)].一种新型抗结核药物:4,4'-二异戊氧基硫代碳酰苯胺(异烟氧酰胺)的临床经验
G Ital Chemioter. 1965 Jan-Dec;12(1):110-20.
4
Clinical data on 4-4' diisoamyloxythiocarbanilide (Isoxyl).4-4' 二异戊氧基硫代碳酰替苯胺(异索克酰)的临床数据。
Antibiot Chemother. 1970;16:128-35. doi: 10.1159/000386813.
5
[Critical remarks on a clinical test of an antitubercular agent. Experiences with thiocarlide during collective work].[关于一种抗结核药临床试验的批判性评论。集体工作中使用硫卡利得的经验]
Prax Pneumol. 1969 Jan;23(1):1-16.
6
[Clinical experimentation of 4-4-diisoamyloxythiocarbanilide in the treatment of pulmonary tuberculosis].
Friuli Med. 1964 Nov-Dec;19(6):935-49.
7
Sputum excretion of tubercle bacilli as early criterion in the evaluation of the therapeutic effectiveness of antituberculous drugs, illustrated by its use in a controlled trial of single-drug regimens.痰液中结核杆菌排出作为评估抗结核药物治疗效果的早期标准,以其在单药治疗方案对照试验中的应用为例。
Antibiot Chemother. 1970;16:490-500. doi: 10.1159/000386851.
8
Clinical experience with thiocarlide (Isoxyl).硫卡利特(异噁酰)的临床经验
Antibiot Chemother. 1970;16:117-23. doi: 10.1159/000386811.
9
A bacteriological study of thiocarlide monotherapy.硫卡利得单一疗法的细菌学研究。
Tubercle. 1969 Sep;50(3):273-9. doi: 10.1016/0041-3879(69)90052-x.
10
[Initial provisional record of a controlled trial of isoniazid-rifomycin-thiocarlide versus isoniazid-streptomycin-thiocarlide in active pulmonary tuberculosis not yet treated].[异烟肼-利福霉素-硫卡利得与异烟肼-链霉素-硫卡利得治疗初治活动性肺结核对照试验的初步临时记录]
Acta Tuberc Pneumol Belg. 1969;60(3):577-82.

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Structural isomerisation affects the antitubercular activity of adamantyl-isoxyl adducts.结构异构化影响金刚烷基异恶唑加合物的抗结核活性。
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Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis.异噻菌胺激活是对结核分枝杆菌产生抑菌活性所必需的。
Antimicrob Agents Chemother. 2007 Nov;51(11):3824-9. doi: 10.1128/AAC.00433-07. Epub 2007 Sep 4.
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EthA, a common activator of thiocarbamide-containing drugs acting on different mycobacterial targets.
EthA是一种作用于不同分枝杆菌靶点的含硫脲药物的常见激活剂。
Antimicrob Agents Chemother. 2007 Mar;51(3):1055-63. doi: 10.1128/AAC.01063-06. Epub 2007 Jan 12.
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Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis.硫脲类药物异烟腙对结核分枝杆菌的独特作用机制。
J Biol Chem. 2003 Dec 26;278(52):53123-30. doi: 10.1074/jbc.M311209200. Epub 2003 Oct 14.
5
Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesis.异噁酰及其新衍生物通过抑制分枝菌酸合成发挥抗分枝杆菌活性。
Antimicrob Agents Chemother. 1999 May;43(5):1042-51. doi: 10.1128/AAC.43.5.1042.
6
[The resistance of Mycobacterium tuberculosis to ethionamide, thiosemicarbazone and isoxyl and their relations to each other].[结核分枝杆菌对乙硫异烟胺、缩氨基硫脲及异烟腙的耐药性及其相互关系]
Beitr Klin Erforsch Tuberk Lungenkr. 1967;134(4):247-58.
7
[Cooperative controlled trial of thiocarlide (DATC), PAS and bedrest alone in short-term single-drug treatment in retreated cavitary pulmonary tuberculosis].[硫卡利得(DATC)、对氨基水杨酸(PAS)及单纯卧床休息在复治空洞型肺结核短期单药治疗中的合作对照试验]
Beitr Klin Erforsch Tuberk Lungenkr. 1969;139(2):115-39.