大剂量阿托品对日常任务执行情况的影响。
The effect of a large dose of atropine upon the performance of routine tasks.
作者信息
Moylan-Jones R J
出版信息
Br J Pharmacol. 1969 Sep;37(1):301-5. doi: 10.1111/j.1476-5381.1969.tb09547.x.
Abstract
- A field trial was conducted in order to assess the effect upon tasks, including hard labour, skilled work, the use of instruments and tools and shooting, of giving 6 mg of atropine sulphate by injection to twenty-three adult male volunteers.2. Impairment of performance was seen in these tasks under the influence of the drug, but this was statistically significant only in some of them.3. Drowsiness occurred in twenty-one men and perceptual disorders were common, but two men were almost completely resistant to the effects of the drug.4. The implications of the therapeutic use of comparable doses of atropine are discussed.
摘要
为评估给23名成年男性志愿者注射6毫克硫酸阿托品对包括重体力劳动、熟练工作、仪器和工具使用以及射击等任务的影响，进行了一项现场试验。
在药物影响下，这些任务的表现出现了损害，但只有其中一些在统计学上具有显著意义。
21名男性出现嗜睡，知觉障碍很常见，但有两名男性几乎完全不受药物影响。
讨论了使用相当剂量阿托品进行治疗的意义。
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