Fedrick J
Br Med J. 1969 Sep 27;3(5673):745-8. doi: 10.1136/bmj.3.5673.745.
The birth weight/gestation distribution of a large series of cases of perinatal death has been analysed according to the lesion (or lesions) present at necropsy. Among the lesions associated with low gestation babies dying with hyaline membranes have a much higher mean birth weight for gestation than either the babies with intraventricular haemorrhage or "no cause found." Among infants dying of intrapartum asphyxia or cerebral birth trauma it was found that those who were stillborn with trauma had, at term, a significantly higher mean birth weight than the control livebirths, and that, at all gestations, the stillbirths with trauma were, on average, heavier than the babies dying neonatally with this lesion. Cases of intrapartum asphyxia were smaller than the stillbirths with trauma, but those dying during the second stage of labour were larger than those dying during the first stage.Cases of intrauterine pneumonia-that is, stillbirths and first-day deaths-were also shown to be larger for length of gestation than cases of extrauterine pneumonia-that is, deaths between the second and the 28th day. The cases with haemorrhagic pneumonia, however, were, at least at term, smaller than the cases of extrauterine pneumonia, and cases of massive pulmonary haemorrhage showed evidence of growth retardation at all gestations.
根据尸检时发现的损伤情况,对一系列围产期死亡病例的出生体重/孕周分布进行了分析。在与孕周较小的婴儿死亡相关的损伤中,患有透明膜病的婴儿平均出生体重比患有脑室内出血或“未发现病因”的婴儿要高得多。在死于产时窒息或脑部产伤的婴儿中,发现足月时因产伤而死产的婴儿平均出生体重显著高于对照活产儿,而且在所有孕周,因产伤而死产的婴儿平均比因这种损伤而在新生儿期死亡的婴儿体重更重。产时窒息病例比因产伤而死产的婴儿小,但在第二产程死亡的病例比在第一产程死亡的病例大。宫内肺炎病例(即死产和出生第一天死亡的病例)的孕周长度也比宫外肺炎病例(即出生第二天至第28天之间死亡的病例)长。然而,出血性肺炎病例至少在足月时比宫外肺炎病例小,而且大量肺出血病例在所有孕周均有生长迟缓的迹象。