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泌乳奶牛子宫内输注抗菌药物后牛奶中药物残留的研究。

A study of drug residues in milk following intrauterine infusion of antibacterial drugs in lactating cows.

作者信息

Black W D, Mackay A L, Doig P A, Claxton M J

出版信息

Can Vet J. 1979 Dec;20(12):354-7.

PMID:534992
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1789638/
Abstract

Intrauterine infusion of nine antibacterial compounds caused detectable drug residues in 17 out of 165 cows or in 25 out of 1110 posttreatment milkings. Four cows treated with pyrolidinomethyl tetracycline suspension had drug residues at the first milking. One cow had residues after oxytetracycline treatment, two after procaine penicillin G, three after acriflavin and after chloramphenicol-dapsone and four after hibitane. Nitrofurazone, nitrofurathiazide and Hibitane Compound(R) did not cause detectable inhibitory residues in any milk sample.

摘要

对165头奶牛进行子宫内输注9种抗菌化合物后,在165头奶牛中的17头或1110次治疗后挤奶中的25次检测到药物残留。4头用吡咯烷甲基四环素悬浮液治疗的奶牛在首次挤奶时就有药物残留。1头奶牛在土霉素治疗后有残留,2头在普鲁卡因青霉素G治疗后有残留,3头在吖啶黄、氯霉素-氨苯砜治疗后有残留,4头在氯己定治疗后有残留。呋喃西林、硝呋噻嗪和复方氯己定在任何牛奶样本中均未检测到抑制性残留。

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本文引用的文献

1
Outline of details for microbiological assays of antibiotics: second revision.
J Pharm Sci. 1971 Nov;60(11):1689-94. doi: 10.1002/jps.2600601122.
2
Oxytetracycline in bovine plasma, milk, and urine after intrauterine administration.
J Dairy Sci. 1976 Feb;59(2):315-7. doi: 10.3168/jds.S0022-0302(76)84201-4.
3
Absorption of antibacterial agents by the bovine involuting uterus.抗菌剂在牛 involuting 子宫中的吸收。
Can Vet J. 1975 Jan;16(1):10-5.