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一名腹泻患者对促胰液素的分泌反应以及胃分泌的卓-艾综合征模式。

Secretory response to secretin in a patient with diarrhoea and the Zollinger-Ellison pattern of gastric secretion.

作者信息

Petersen H, Myren J, Liavåg I

出版信息

Gut. 1969 Oct;10(10):796-9. doi: 10.1136/gut.10.10.796.

DOI:10.1136/gut.10.10.796
PMID:5350104
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1553005/
Abstract

In a woman with diarrhoea and the Zollinger-Ellison pattern of gastric secretion, the secretion of fluid and bicarbonate into the duodenum in response to secretin was found to be significantly greater than in controls. No pancreatic tumour was found at operation. The pancreas was, however, larger than normal. The patient did not show symptoms of peptic ulcer disease until vagotomy and pyloroplasty had been performed. A capacity to secrete large amounts of bicarbonate was believed to be the explanation of why she was able to tolerate great amounts of acid.

摘要

在一名患有腹泻且具有卓-艾氏胃分泌模式的女性患者中,发现其对促胰液素的反应是向十二指肠分泌的液体和碳酸氢盐显著多于对照组。手术时未发现胰腺肿瘤。然而,胰腺比正常情况大。该患者在进行迷走神经切断术和幽门成形术之前未表现出消化性溃疡疾病的症状。能够分泌大量碳酸氢盐被认为是她能够耐受大量胃酸的原因。

相似文献

1
Secretory response to secretin in a patient with diarrhoea and the Zollinger-Ellison pattern of gastric secretion.一名腹泻患者对促胰液素的分泌反应以及胃分泌的卓-艾综合征模式。
Gut. 1969 Oct;10(10):796-9. doi: 10.1136/gut.10.10.796.
2
Effect of cholecystokinin and secretin on gastric hypersecretion in a patient with the Zollinger-Ellison syndrome.
Aust N Z J Med. 1972 Nov;2(4):393-6. doi: 10.1111/j.1445-5994.1972.tb03943.x.
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Am J Dig Dis. 1978 Dec;23(12):1089-97. doi: 10.1007/BF01072884.
4
[PANCREAS AND PEPTIC ULCER].
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Effect of vagotomy and pyloroplasty on pancreatic dose-response curves to secretin in man.迷走神经切断术和幽门成形术对人体胰腺对促胰液素剂量反应曲线的影响。
Am J Dig Dis. 1971 Dec;16(12):1087-90. doi: 10.1007/BF02235165.
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Pancreatic function in patients with the Zollinger-Ellison syndrome. Observations concerning acid-bicarbonate secretion ratios.佐林格-埃利森综合征患者的胰腺功能。关于酸-碳酸氢盐分泌比率的观察结果。
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The hypersecretory states of the pancreas. Implications in the pathophysiology of pancreatic inflammation and the pathogenesis of peptic ulcer diathesis.
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本文引用的文献

1
THE EXPERIMENTAL PRODUCTION OF PEPTIC ULCER.消化性溃疡的实验性产生
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2
Zollinger-Ellison syndrome with diarrhoea and malabsorption. Observations on a patient before and after pancreatic islet-cell tumour removal with-out resort.伴有腹泻和吸收不良的佐林格-埃利森综合征。对一例胰岛细胞瘤切除术前及术后未使用[具体药物,原文未提及]的患者的观察。
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3
Mechanism of the disordered physiology involved in the Zollinger-Ellison syndrome. Report of a case.佐林格-埃利森综合征所涉及的生理紊乱机制。病例报告。
Am J Dig Dis. 1962 May;7:401-19. doi: 10.1007/BF02232360.
4
Malabsorption and jejunal ulceration due to gastric hypersecretion with pancreatic islet-cell hyperplasia.由于胃分泌过多伴胰岛细胞增生导致的吸收不良和空肠溃疡。
Lancet. 1959 Jan 17;1(7064):120-3. doi: 10.1016/s0140-6736(59)90003-0.
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Steatorrhea associated with ulcerogenic tumor of the pancreas.与胰腺致溃疡肿瘤相关的脂肪泻。
Am J Med. 1958 Sep;25(3):456-9. doi: 10.1016/0002-9343(58)90085-8.
6
Gastric hypersecretion, peptic ulceration and islet-cell tumor of the pancreas (the Zollinger-Ellison syndrome); report of a case and review of the literature.胃分泌过多、消化性溃疡与胰腺胰岛细胞瘤(佐林格-埃利森综合征):一例报告并文献复习
N Engl J Med. 1957 Nov 14;257(20):965-70. doi: 10.1056/NEJM195711142572003.
7
Effect of large doses of histamine on gastric secretion of HCI; an augmented histamine test.大剂量组胺对胃酸分泌的影响;组胺增强试验
Br Med J. 1953 Jul 11;2(4827):77-80. doi: 10.1136/bmj.2.4827.77.
8
The effect of secretin on gastric acid secretion and peptic ulcers induced by pentagastrin in cats with intact or resected duodenum.在十二指肠完整或切除的猫中,促胰液素对五肽胃泌素诱导的胃酸分泌和消化性溃疡的影响。
Am J Dig Dis. 1968 Oct;13(10):874-81. doi: 10.1007/BF02237572.
9
The isolation and chemistry of secretin and cholecystokinin.促胰液素与缩胆囊素的分离及化学性质
Gastroenterology. 1968 Aug;55(2):157-64.
10
Physiologic responses to gastric acid hypersecretion in Zollinger-Ellison syndrome.
Am J Dig Dis. 1968 Mar;13(3):191-203. doi: 10.1007/BF02236593.