Lucchetti V
Chir Ital. 1979 Apr;31(2):226-33.
This clinical trial was designed to assess the validity of an association of equal parts of ampicillin and flucloxacillin in surgical patients; the product was administered by injection in daily doses of 2-3 grams. In a group of 20 patients the same product was used prophylactically against infection, with positive results in 85% of the cases; the mean duration of treatment was 5 days. In 13 patients affected by urinary and biliary infections the product was effective. After a 7 days-therapy, 11 cases showed a marked improvement of the clinical symptomatology. Allergic cutaneous reactions (rashes, itching) appeared in five cases. No other side-effects had been noticed.
本临床试验旨在评估等量氨苄西林和氟氯西林联合用药在外科手术患者中的有效性;该产品通过注射给药,每日剂量为2 - 3克。在一组20名患者中,使用该产品预防感染,85%的病例取得了阳性结果;平均治疗持续时间为5天。在13例患有泌尿系统和胆道感染的患者中,该产品有效。经过7天的治疗,11例患者的临床症状明显改善。5例出现了过敏性皮肤反应(皮疹、瘙痒)。未发现其他副作用。