Demin A A, Semenova L A, Tomsons V P, Krylov B V, Fofanova G G
Cor Vasa. 1979;21(3):208-14.
RNA preparations were used as stimulants of reparative processes in rat myocardium damaged by diathermocoagulation. Administration of RNA accelerated the proteosynthesis in the zone of the lesion, as indicated by the intensity of incorporation of 14C-labelled amino-acids. Morphological examinations of the myocardium revealed increased synthetic activity in fibroblasts, proliferation of fibroblasts, and accelerated scar healing. The results prove the stimulating effect of RNA preparations on reparative processes in the damaged myocardium.
RNA制剂被用作促进因透热凝固而受损的大鼠心肌修复过程的刺激物。如14C标记氨基酸的掺入强度所示，RNA的施用加速了损伤区域的蛋白质合成。对心肌的形态学检查显示，成纤维细胞的合成活性增加、成纤维细胞增殖以及瘢痕愈合加速。结果证明了RNA制剂对受损心肌修复过程的刺激作用。
