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In vivo measurement of 5-hydroxytryptamine turnover rate in the rat brain from the conversion of C14-tryptophan to C14-5-hydroxytryptamine.

作者信息

Lin R C, Costa E, Neff N H, Wang C T, Ngai S H

出版信息

J Pharmacol Exp Ther. 1969 Dec;170(2):232-8.

PMID:5355978
Abstract
摘要

相似文献

1
In vivo measurement of 5-hydroxytryptamine turnover rate in the rat brain from the conversion of C14-tryptophan to C14-5-hydroxytryptamine.通过C14-色氨酸向C14-5-羟色胺的转化对大鼠脑内5-羟色胺周转率进行体内测量。
J Pharmacol Exp Ther. 1969 Dec;170(2):232-8.
2
P-chloroamphetamine: in vivo investigations on the mechanism of action of the selective depletion of cerebral serotonin.对氯苯丙胺：关于脑内5-羟色胺选择性耗竭作用机制的体内研究
J Pharmacol Exp Ther. 1970 Nov;175(2):419-26.
3
Effects of acutely administered analgesic drugs on rat brain 5-hydroxytryptamine turnover.急性给予镇痛药物对大鼠脑5-羟色胺代谢的影响。
Br J Pharmacol. 1972 Nov;46(3):562P-563P.
4
Biogenic amines and narcotic effects. II. Serotonin turnover in the rat after acute and chronic morphine administration.生物胺与麻醉作用。II. 急性和慢性给予吗啡后大鼠体内血清素的周转情况。
J Pharmacol Exp Ther. 1973 May;185(2):328-35.
5
Effects of acute cocaine treatment on the turnover of 5-hydroxytryptamine in the rat brain.急性可卡因处理对大鼠脑内5-羟色胺更新率的影响。
Br J Pharmacol. 1975 May;54(1):61-4. doi: 10.1111/j.1476-5381.1975.tb07410.x.
6
Turnover rate measurements of brain serotonin in unanesthetized rats.未麻醉大鼠脑血清素周转率的测量
Adv Biochem Psychopharmacol. 1969;1:91-109.
7
The effects of drugs on serotonergic nerve terminals.
Adv Cytopharmacol. 1971 May;1:379-95.
8
Effect of acute and chronic administration of ethanol on the 5-hydroxytryptamine turnover and tryptophan hydroxylase activity of the mouse brain.急性和慢性给予乙醇对小鼠脑内5-羟色胺代谢及色氨酸羟化酶活性的影响。
Brain Res. 1971 Mar 5;26(2):450-4.
9
Labelled 5-hydroxytryptamine and 5-hydroxyindoleacetic acid formed in vivo from 3H-tryptophan in rat brain effect of probenecid.大鼠脑中由3H-色氨酸在体内生成的标记5-羟色胺和5-羟吲哚乙酸：丙磺舒的作用
Acta Physiol Scand. 1974 Feb;90(2):401-8. doi: 10.1111/j.1748-1716.1974.tb05601.x.
10
Inhibition of the biosynthesis of 5-hydroxytryptamine in rat brain by imipramine.丙咪嗪对大鼠脑内5-羟色胺生物合成的抑制作用。
Eur J Pharmacol. 1972 Nov;20(2):231-7. doi: 10.1016/0014-2999(72)90153-7.

引用本文的文献

1
Serotonin biosynthesis as a predictive marker of serotonin pharmacodynamics and disease-induced dysregulation.血清素生物合成作为血清素药效学和疾病诱导失调的预测标志物。
Sci Rep. 2016 Jul 21;6:30059. doi: 10.1038/srep30059.
2
Acute and chronic tryptophan depletion differentially regulate central 5-HT1A and 5-HT 2A receptor binding in the rat.急性和慢性色氨酸耗竭对大鼠中枢5-羟色胺1A和5-羟色胺2A受体结合的调节作用不同。
Psychopharmacology (Berl). 2007 Mar;190(4):497-506. doi: 10.1007/s00213-006-0635-5. Epub 2006 Nov 24.
3
Alpha-methyl-L-tryptophan as a tracer to study brain serotonergic system.
α-甲基-L-色氨酸作为研究脑血清素能系统的示踪剂。
Neurochem Res. 1995 Nov;20(11):1353-60. doi: 10.1007/BF00992511.
4
Studies on the mechanism of shock. Central serotoninergic neuron activity after trauma in the rat.休克机制的研究。大鼠创伤后中枢5-羟色胺能神经元活动
Br J Exp Pathol. 1980 Feb;61(1):61-8.
5
Effects of synthesis inhibition and nervous activity on concentrations of neuronal substance P.合成抑制和神经活动对神经元P物质浓度的影响。
Naunyn Schmiedebergs Arch Pharmacol. 1983 Jun;323(2):173-5. doi: 10.1007/BF00634267.
6
Effect of environmental temperature on the turnover of 5-hydroxytryptamine in various areas of rat brain.环境温度对大鼠脑不同区域5-羟色胺代谢的影响。
J Physiol. 1970 Nov;211(1):93-108. doi: 10.1113/jphysiol.1970.sp009268.
7
Rapid accumulation of H3-serotonin in brains of rats receiving intraperitoneal H3-tryptophan: effects of 5,6-dihydroxytryptamine or female sex hormones.腹腔注射H3-色氨酸的大鼠脑内H3-5-羟色胺的快速蓄积：5,6-二羟基色胺或雌性激素的影响
J Neural Transm. 1973;34(2):111-24. doi: 10.1007/BF01244664.
8
Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase.使用芳香族氨基酸脱羧酶抑制剂在体内同时测量大脑中酪氨酸羟化酶和色氨酸羟化酶的活性。
Naunyn Schmiedebergs Arch Pharmacol. 1972;275(2):153-68. doi: 10.1007/BF00508904.
9
Estimation of the rate of 5-HT synthesis in the mouse brain by various methods.用各种方法估算小鼠大脑中5-羟色胺（5-HT）的合成速率。
Naunyn Schmiedebergs Arch Pharmacol. 1974;282(3):223-38. doi: 10.1007/BF00501231.
10
Probenecid-induced increase of 5-hydroxytryptamine synthesis in rat brain, as measured by formation of 5-hydroxytryptophan.通过5-羟色氨酸的生成来测定，丙磺舒诱导大鼠脑内5-羟色胺合成增加。
Psychopharmacology (Berl). 1979 Feb 28;60(3):229-35. doi: 10.1007/BF00426660.