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喉内注射类固醇激素在声门下狭窄保守治疗中的应用

Intralesional steroids in conservative management of subglottic stenosis of the larynx.

作者信息

Gnanapragasam A

出版信息

Int Surg. 1979 Apr;64(3):63-7.

PMID:536159
Abstract

Subglottic stenosis after prolonged endotracheal intubation is a well recognised complication, especially with the advent of intensive resuscitative techniques. Although prevention is the best cure, once the management has been established it should be conservative in the first instance, especially in the case of children. The successful treatment of four cases with this complication is reported. The treatment consisted of intralesional injection of Triamcinolone Acetonide Aqueous Suspension (Kenacort A), dilatation with gum elastic bougies, bronchoscopy and very limited surgical correction in one case. A brief reference is made to the etiological factors and to the mechanism of action of steroids in scar tissue.

摘要

长时间气管插管后声门下狭窄是一种公认的并发症,尤其是随着强化复苏技术的出现。尽管预防是最佳治疗方法,但一旦确定治疗方案,首先应采取保守治疗,尤其是对于儿童患者。本文报道了4例该并发症的成功治疗案例。治疗方法包括病灶内注射曲安奈德水混悬液(康宁克通A)、用弹性树胶探条扩张、支气管镜检查,其中1例进行了非常有限的手术矫正。文中简要提及了病因及类固醇在瘢痕组织中的作用机制。

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