Studies on the responses of different types of muscle fibre during surgically induced compensatory hypertrophy.

The sizes of the different types of muscle fibre in the extensor digitorum longus (EDL) muscles of mice have been measured, EDL muscles showing compensatory hypertrophy following the removal of the tibialis anterior muscle 116 days previously being compared with normal contralateral controls. Contrary to previous findings, the hypertrophy was well maintained after 116 days and Type II fibres were enlarged preferentially.