Dussault J, Plamondon C, Volpe R
Can Med Assoc J. 1969 Dec 27;101(13):51-6.
Two patients suffering from aneurysms of the internal carotid artery simulating pituitary tumours are reported. One of these was a 17-year-old boy with a mycotic aneurysm of the right internal carotid artery causing failure of growth and pubertal maturation. The second was a 53-year-old woman with a left internal carotid artery aneurysm, probably of atherosclerotic origin, who had evidence of anterior pituitary insufficiency.In both cases there was paresis of extraocular muscles and one patient had bitemporal hemianopsia. While lateral radiographs of the skull suggested intrasellar calcification in each case, further roentgenological investigation established that this calcification was actually extrasellar, and carotid arteriograms demonstrated the presence of an internal carotid aneurysm in each case. Investigations of the endocrine system confirmed the presence of anterior pituitary insufficiency in both patients, and diabetes insipidus became evident in one patient after cortisone therapy was commenced.This lesion, while rare, may be difficult to differentiate from a pituitary tumour. It is likely that this syndrome depends on aneurysmal expansion to the region of the sella turcica with compression of the pituitary gland itself, as well as the optic fibres.
报告了两名患有模拟垂体瘤的颈内动脉瘤患者。其中一名是17岁男孩，患有右侧颈内动脉霉菌性动脉瘤，导致生长发育和青春期成熟障碍。另一名是53岁女性，患有左侧颈内动脉瘤，可能起源于动脉粥样硬化，有垂体前叶功能减退的证据。在这两个病例中均有眼外肌麻痹，其中一名患者有双颞侧偏盲。虽然颅骨侧位片在每个病例中均提示鞍内钙化，但进一步的放射学检查证实这种钙化实际上位于鞍外，颈动脉造影显示每个病例中均存在颈内动脉瘤。内分泌系统检查证实两名患者均存在垂体前叶功能减退，在一名患者开始使用可的松治疗后出现了尿崩症。这种病变虽然罕见，但可能难以与垂体瘤相鉴别。这种综合征可能是由于动脉瘤扩展至蝶鞍区域，压迫垂体本身以及视神经纤维所致。
