胃复安对犬小肠转运的影响。
Effect of metoclopramide on transport in the small intestine of the dog.
作者信息
Tinker J, Cox A G
出版信息
Gut. 1969 Dec;10(12):986-9. doi: 10.1136/gut.10.12.986.
Abstract
A method is described for the simultaneous measurement of flow rate, mean transit time, and volume of the intestine during the transport of fluid through a segment of the small intestine of the dog. Using this method, the effect of metoclopramide on motility of the small bowel was assessed. The drug resulted in a decrease in transit time and volume in the test segment of bowel while the flow rate remained constant. This finding suggests that metoclopramide-stimulated contraction of intestinal smooth muscle.
摘要
描述了一种在液体通过狗小肠段运输过程中同时测量小肠流速、平均通过时间和容积的方法。使用该方法，评估了甲氧氯普胺对小肠运动的影响。该药物导致受试肠段的通过时间和容积减少，而流速保持恒定。这一发现表明甲氧氯普胺刺激了肠道平滑肌的收缩。
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