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倍他米松的产前给药。对早产儿新生儿血糖的影响(作者译)

[Antenatal administration of betamethasone. Effects upon neonatal blood glucose in premature infants (author's transl)].

作者信息

Sann L, Burnod J, Lasne Y, Bethenod M

出版信息

Nouv Presse Med. 1979 Oct 15;8(39):3147-8.

PMID:537873
Abstract

This effect was studied in 23 preterm neonates at the age of 2--8 hours. Betamethasone was administered at a dose of 12 mg intramuscular once or several times before delivery. This glycemia was compared with the glycemia of 52 control preterm infants studied at the same period. In the control preterm neonates, the mean (+/- 1 S.D.) blood glucose level was 0.51 +/- 0.26 g/l versus 0.53 +/- 0.24 g/l in the preterm infants pretreated with betamethasone. The incidence of glycemia less than 0.30 or 0.20 g/l was not significantly different in the two groups. These data show that prenatal betamethasone therapy has no harmful or diserable effect on the neonatal glycemia of preterm infants.

摘要

在23名2至8小时大的早产新生儿中研究了这种效应。在分娩前,倍他米松以12毫克的剂量肌肉注射一次或多次。将这些新生儿的血糖水平与同期研究的52名对照早产婴儿的血糖水平进行比较。在对照早产新生儿中,平均(±1标准差)血糖水平为0.51±0.26克/升,而接受倍他米松预处理的早产婴儿为0.53±0.24克/升。两组中血糖水平低于0.30或0.20克/升的发生率无显著差异。这些数据表明,产前倍他米松治疗对早产婴儿的新生儿血糖没有有害或有益影响。

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