Parfrey P S, Turnbull A L, Pollock D J, Barnett M
Postgrad Med J. 1979 Oct;55(648):747-50. doi: 10.1136/pgmj.55.648.747.
Iron overload was found in 3 patients who had undergone partial gastrectomy: a 61-year-old woman developed iron overload because she may have had idiopathic haemochromatosis and had also been given parenteral iron; in a 62-year-old man with thalassaemia minor, iron overload may have developed because of increased oral iron ingestion, low serum folate, increased, albeit ineffective, erythropoiesis and sideroblastic anaemia; a 74-year-old man with thalassaemia minor developed iron overload without exogenous therapy and died from a hepatoma. These cases illustrate that partial gastrectomy fails to protect patients from developing iron overload, particularly if given uncontrolled iron therapy.
在3例接受过胃部分切除术的患者中发现了铁过载:一名61岁女性出现铁过载,可能是因为她患有特发性血色素沉着症且接受过胃肠外铁剂治疗;一名62岁轻度地中海贫血男性出现铁过载,可能是由于口服铁摄入量增加、血清叶酸水平低、红细胞生成增加(尽管无效)以及铁粒幼细胞性贫血;一名74岁轻度地中海贫血男性在未接受外源性治疗的情况下出现铁过载,并死于肝癌。这些病例表明,胃部分切除术不能保护患者免于发生铁过载,特别是在铁剂治疗不受控制的情况下。