Kirk D N, Sá e Melo M L
Steroids. 1979;34(6 Spec no):683-92. doi: 10.1016/0039-128x(79)90138-7.
The compounds named in the title were prepared by routes which included the reduction of suitable 16 alpha,17-epoxypregnan-20-ones with aluminium amalgam to give 16 alpha-hydroxypregnan-20-ones, and reduction of the 20-oxo function either with sodium borohydride to obtain the 3,16 alpha,20 beta-triols or with lithium-liquid ammonia to obtain the 3,16 alpha,20 alpha-triols.
标题中所命名的化合物是通过以下路线制备的，这些路线包括用铝汞齐还原合适的16α,17 - 环氧孕甾 - 20 - 酮以得到16α - 羟基孕甾 - 20 - 酮，以及用硼氢化钠还原20 - 氧代官能团以获得3,16α,20β - 三醇，或用锂 - 液氨还原以获得3,16α,20α - 三醇。
