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多头绒泡菌“G2期”核仁相关DNA的复制

Replication of nucleolus-associated DNA during "G2 phase" in Physarum polycephalum.

作者信息

Guttes E, Guttes S

出版信息

J Cell Biol. 1969 Nov;43(2):229-36. doi: 10.1083/jcb.43.2.229.

Abstract

In the myxomycete, Physarum polycephalum, the bulk of nuclear DNA replication occurs during a period of a few hours immediately following upon mitosis. During the remainder of the intermitotic period, incorporation of thymidine-(3)H continues at a low rate in the region of the nucleolus (radioautographs). A few nuclei incorporated thymidine-(3)H into the extranucleolar chromatin at a high rate at all times of the intermitotic period. These nuclei were exceptionally large and they frequently contained several small nucleoli of different sizes rather than the one, central nucleolus which is characteristic of a normal interphase nucleus.

摘要

在黏菌多头绒泡菌中,大部分核DNA复制发生在有丝分裂后紧接着的几个小时内。在有丝分裂间期的其余时间里,胸腺嘧啶核苷 -(3)H在核仁区域以较低速率持续掺入(放射自显影片)。在有丝分裂间期的所有时间里,少数细胞核以高速率将胸腺嘧啶核苷 -(3)H掺入核仁外染色质。这些细胞核异常大,并且它们经常含有几个不同大小的小核仁,而不是正常间期细胞核特有的一个中央核仁。

相似文献

2
Continuous nucleolar DNA synthesis after inhibition of mitosis in Physarum polycephalum.
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Control of RNA transcription in nuclei and nucleoli of Physarum polycephalum.
FEBS Lett. 1978 Feb 15;86(2):303-6. doi: 10.1016/0014-5793(78)80585-7.

本文引用的文献

1
Nucleic acid metabolism in a slime mold with synchronous mitosis.具有同步有丝分裂的黏菌中的核酸代谢。
Biochim Biophys Acta. 1960 Feb 26;38:298-306. doi: 10.1016/0006-3002(60)91245-2.
3
RNA SYNTHESIS IN THE MITOTIC CYCLE OF PHYSARUM POLYCEPHALUM.多头绒泡菌有丝分裂周期中的RNA合成
Biochim Biophys Acta. 1964 Nov 15;91:399-405. doi: 10.1016/0926-6550(64)90069-6.
6
Chromosome damage induced by hydroxylamine in mammalian cells.羟胺对哺乳动物细胞造成的染色体损伤。
Proc Natl Acad Sci U S A. 1962 Jun 15;48(6):937-43. doi: 10.1073/pnas.48.6.937.
10
The mode of chromosome duplication in Crepis capillaris.毛茛叶还阳参中染色体复制的模式。
Exp Cell Res. 1958 Oct;15(2):350-7. doi: 10.1016/0014-4827(58)90036-3.

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