Piantadosi C A, Clinton R L, Thalmann E D
Undersea Biomed Res. 1979 Dec;6(4):347-56.
Twenty-four oxygen exposures lasting 80 to 271 min were performed by six immersed exercising subjects at 25 fsw (1.76 ATA) in both warm and cold water. Two types of exercise were performed, moderate work (50 watts) for long periods of time, and graded exercise (25-150 watts) lasting 85 min. In 21 degrees C water, moderate exercise lasted 228 +/- 39 min, with a mean VO2 of 1.72 +/- 0.11 liter/min. In 4 degree C water, the duration was 163 +/- 22 min, with a mean VO2 of 1.83 +/- 0.16 liter/min. The differences in duration of oxygen exposure in warm and cold water reflect termination at an inspired PCO2 of 7.6 mmHg, a level reached earlier in cold water because of CO2 absorbent exhaustion. In 21 degrees C water, the VO2 for graded exercise ranged from 1.51 to 3.00 liter/min and in 4 degrees C water, from 2.00 to 3.16 liter/min. Central nervous system oxygen toxicity was not observed during these exposures, although two divers had clinical and spirometric evidence of early pulmonary oxygen toxicity. The absence of CNS oxygen toxicity is attributed to low resistance and minimization of dead space, which caused a low inspired PCO2, although the divers' experience with oxygen diving and their excellent physical condition may have contributed as well.
六名浸泡在水中的运动受试者在25英尺海水深度(1.76绝对大气压)的温水和冷水中进行了24次持续80至271分钟的吸氧试验。进行了两种类型的运动,长时间的中等强度运动(50瓦)和持续85分钟的分级运动(25 - 150瓦)。在21摄氏度的水中,中等强度运动持续228±39分钟,平均摄氧量为1.72±0.11升/分钟。在4摄氏度的水中,持续时间为163±22分钟,平均摄氧量为1.83±0.16升/分钟。温水和冷水中吸氧持续时间的差异反映出当吸入二氧化碳分压达到7.6毫米汞柱时试验终止,由于二氧化碳吸收剂耗尽,在冷水中该水平更早达到。在21摄氏度的水中,分级运动的摄氧量范围为1.51至3.00升/分钟,在4摄氏度的水中,为2.00至3.16升/分钟。在这些试验过程中未观察到中枢神经系统氧中毒,尽管有两名潜水员有早期肺氧中毒的临床和肺功能证据。未出现中枢神经系统氧中毒归因于低阻力和死腔最小化,这导致吸入二氧化碳分压较低,尽管潜水员的氧气潜水经验和良好的身体状况也可能起到了一定作用。